Lipid Nanoparticles

Lipid-based nanoparticle systems include various formulations such as lipid nanoparticles (LNPs), liposomes, solid lipid nanoparticles (SLNs), and nanostructured lipid carriers (NLCs), and are widely used in pharmaceutical formulation, nucleic acid delivery, vaccine development, and nanomedicine research.

Lipid Nanoparticle Formulation Technologies

Different lipid nanoparticle formulations may require different processing approaches. Genizer provides three main solutions to support lipid nanoparticle development from laboratory research through process scale-up and manufacturing.

Microfluidic Mixing

NanoMixer enables controlled and reproducible mixing of lipid and aqueous phases for laboratory-scale LNP formulation, including mRNA, DNA, and siRNA delivery systems.

High Pressure Homogenization

High pressure homogenizers are used for particle size reduction, dispersion, and particle size control of certain lipid nanoparticle formulations, from laboratory to production scale.

Liposome Extrusion

Liposome extruders use defined-pore membranes for particle size control and improved size uniformity in liposomes and certain lipid-based nanoparticle formulations.