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Ultra High Pressure Homogenizer UltraGenizer

Description: High Shear Liquid Homogenizer for lipid nanoparticles preparation (up to 60,000 psi)
Catalog Number: UltraGenizer
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  • Pressure:
  • Flow Rate:
  • Syringe Inlet&Outlet:
    10mL*2 20mL*2 50mL*2 100mL*2 200mL*2 500mL*2
  • Option: Inlet Stainless Cylinder:
    None 500mL 1000mL 2000mL 300mL-Glass-Jacketed
  • Option: Heat Exchanger:
    None HPE-100 HPE-150 HPE-150-3D
  • Voltage:
    380V 415-440V
  • Warranty:
    Standard 1 year 2 year 3 year 4 year 5 year
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  • Description
  • How to Use
  • FAQ and Tips
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UltraGenzier High Shear Homogenizer:
UltraGenizer is a laboratory ultra high pressure processing equipment. It is an electrically-driven and bench-top high shear homogenizer, which requires no compressed air and no hydraulic oil to achieve maximum 4,200 bar (60,000 psi) operating pressure.
Application of UltraGenzier High Shear Homogenizer:
Nano Emulsions 
Nano Dispersions
Performance of UltraGenzier High Shear Homogenizer:
Energy efficient, 1/2 energy loss of the most homogenizers
Small (Integrated design delivers the light weight and small dimensions)
Smart (Programming control systems confer diligent functions: Controlled inlet volume±0.1mL; Auto stop with time/volume)
Silent (Noiseless performance )
Strong (More than 120 mL/min at 60,000 psi)
CE compliant and RoHs compliant
Catalog No. Ultra60K
Flow Rate 120mL/min
Min. Sample 5mL
Max. Pressure 60,000psi
Dimensions(cm) 130 × 40 × 35
Weight 112 kg (247 lbs)
Max. Temp. 80ºC (176ºF)
Power 380V/430V
Cleaning Flush to clean
Application Nano emulsion, Fat emulsion, Liposome, Cell disruption, Nano dispersion, Deagglomeration, Nanoparticle, Graphene
Features Digital display of pressure or pressure gauge
Standard Features
Parts ultra Y-type Diamond interaction chamber with cooling option
Control System High pressure programming control systems®: Touch Screen, Speed control, Auto stop control by volume, time, pressure or temperature, Settable volume control as low as 1mL, Display of flow rate and time, Overload protection
Pressure Gauge Digital display on the touch screen
Inlet Type 3/8" HP coupling
Outlet Type 3/8" HP coupling
Inlet Reservoir 100mL Syringe
Outlet Reservoir 100mL Syringe
Product Material 316L Stainless Steel, Tungsten Carbide, Viton, Teflon
Material Standard Pharmaceutical Grade, FDA, GMP
Warranty 1 year against any manufacturing defects
Option Features
Parts High Pressure Extruders, Homogenizing Valves Two Stages, Heat Exchanger
Control System Mechanical control: speed, start, stop control
Detector Pressure gauge, Pressure transducer up to 8 optional, Temperature transducer up to 8 optional
Outlet Type Tri-clamp or Luer
Heat Exchanger HPE-100-3D; HPE-150-3D; HPE-200-3D
LiposomeExtruder GOE-200mL; GOE-1000mL
Inlet Reservoir 10mL, 20mL, 50mL, 100mL, 200mL, 500mL Syringe, S/S Cylinder, Jacketed Glass Cylinder or Online
Outlet Reservoir 10mL, 20mL, 50mL, 100mL, 200mL, 500mL Syringe, S/S Cylinder, Jacketed Glass Cylinder or Online
Cylinder Titanium High Pressure Cylinder (Resistant to strong acid and base)
Varieties of Inlet and Outlet for Ultragenizer
Inlet:  Syringe; Open Container; Stainless Steel Cylinder
Outlet: Syringe; Open Container; Stainless Steel Cylinder
High Pressure Homogenizer Inlet and Outlet
Disassemble the seal

Assemble the seal
Our design has minimized the occurrence of the air-blocking, chamber-blocking and overload.
However, the improper operation of the homogenizer can still induce the error and damage of the homogenizer.

Air Blocking
Symptom: There is no pressure or there is no sucking from inlet
Prevention: Do not run with empty inlet
Reason: There is air inside the pump
1) In the Customer setup, push the button: Degas
2) Running 50mL water with 50% speed
3) Push the Ball in the inlet valve with a pin

Chamber Blocking
Symptom: Overload of the pressure
Prevention: Pre-treat the sample carefully; Reduce the speed
Reason: There is aggregates or particles in the sample; Too much speed
1) Reverse flow the outlet valve with 100mL water with low speed
2) Reverse flow the Chamber with water from low to high speed

1) Reduce the speed and close the power, wait 30 sec and restart again
2) Wash with water or your solvent
3) Running with clean and homo-disperse sample

The air blocking has rare damage for the Nanogenizer, however the chamber blocking is harmful to the pump because of overloaded pressure in an instant.
1) Pretreat the sample carefully, and always use clean and homo-disperse sample,
2) Adjust the pressure from low to high.
3) For safety, don not point the inlet or outlet of high pressure devices and equipment’s supplied by the Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel and object which may induce the safety issue and property loss.

For facilitating the user applications, the two ports in the high pressure cylinder of NanoGenizer is exchangeable for inlet and outlet.

Cells Mammalian cell
Insect cell Bacteria cell Yeast cell Algae cell SPore
Sample CHO|Hela Sf9|Sf21|H5 E. Coli   Yeast Green algaea Ganoderma
Pressure 600-800bar   8500-11500psi 600-1000bar 8500-14500psi 800-1000bar 11500-14500psi 1200-1400bar 17500-20000psi 1200-1500bar 7500-21500psi 1300-1600bar 18500-23000psi
Chamber F20Y, F20Y-RT F20Y, F20Y-RT F20Y, F20Y-RT F20Y, F12Y F20Y, F12Y F20Y, F12Y

Emulsions Oil in water emulsions
Water in oil emulsions Oil emulsion Food Liposome (o/w) Liposome (w/o)
Sample Fat emulsion| Prostaglandin Cosmetics Dimethicone|Fuel Milk Doxorubicin DNA|lipopolyplex
Pressure ~20,000psi ~10,000psi ~20,000psi ~10,000psi ~20,000psi ~8,000psi
Chamber F20Y, F12Y F20Y F20Y, F12Y F20Y F20Y, F12Y F20Y

Dispersions Pigments
Drugs/Creams Battery Particle aggregation Graphene Nanotubes
Sample Inks, Coatings Norfloxacin, Isoxyl Lithium/Solar cell Nano fibril Graphene Carbon Nanotubes
Pressure ~25,000psi ~20,000psi ~20,000psi ~25,000psi ~20,000psi ~20,000psi
Chamber F20Y, F12Y F20Y, F12Y F20Y, F12Y F20Y, F12Y F20Y, F12Y F20Y, F12Y
1. Order the unit from your Local Agent (Recommended)

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4. Order and pay online from the website if the Total Amount <$3000.00