Description:
A homogenizer designed especially for mixing and homogenizing the sample fluids from two or more inlet ports.
Application:
Nanodispersions, nanoemulsions and nanotube
Cell disruption
Micro/nanoencapsulation in polymers, liposomes and oils
Solid dispersion and suspension, deagglomeration
Performance:
Energy efficient, 1/2 energy loss of the most homogenizers
Small (integrated design delivers the light weight and small dimensions)
Smart (programming control systems confer diligent functions: controlled inlet volume ± 0.1mL; auto stop with time/volume)
Silent (noiseless performance)
Strong (more than 240 mL/min at 30,000 psi)
CE compliant and RoHS compliant
| Specifications |
| Catalog No. |
MixGenizer-30k |
| Max. Flow Rate |
240 mL/min |
| Min. Sample |
1 mL |
| Max. Pressure |
30,000 psi |
| Dimensions(cm) |
85×53×37 |
| Weight |
58 kg (128lbs) |
|
| Max. Temp. |
80 ºC (176 ºF) |
| Power |
220 V/110 V |
| Cleaning |
Flush to clean |
| Application |
Nano emulsion, fat emulsion, liposome, cell disruption, nano dispersion, deagglomeration, nano precipitations |
| Features |
Notable shear rate; powerful micromix; greater repeatability; guaranteed scalability |
| |
| Standard Features |
| Parts |
Diamond Mixing Chamber |
| Control System |
High pressure programming control systems: touch screen, speed or pressure control, auto stop control by volume, time, pressure or temperature, settable volume control as small as 1mL, display of flow rate and time, overload protection |
| Pressure Gauge |
Digital display on the touch screen |
| Inlet Type |
1/4" HP coupling or 3/8" HP coupling |
| Outlet Type |
1/4" HP coupling or 3/8" HP coupling |
| Mixing Accuracy |
1% |
| Mixing Arrange |
1%~100% : 100% |
| Inlet Reservoir |
100 mL syringe or S/S cylinder |
| Outlet Reservoir |
100 mL syringe |
| Product Material |
316L stainless steel, zirconia ceramic, viton, teflon |
| Material Standard |
Sanitary grade, FDA, GMP |
| Warranty |
1 year against any manufacturing defects |
| |
| Option Features |
| Parts |
High pressure extruders, Y-type diamond mixing chamber with cooling, heat exchanger |
| Control System |
Gradient mixing, three or four components |
| Detector |
Pressure gauge, pressure transducer up to 8 options, temperature transducer up to 8 options |
| Outlet Type |
Tri-clamp, luer or flow sorter |
| Heat Exchanger |
HPE-100-3D; HPE-150-3D; HPE-200-3D |
| Inlet Reservoir |
20mL, 50mL, 100mL, 200mL syringe, 300mL, 500mL S/S cylinder, jacketed glass cylinder or online |
| Outlet Reservoir |
20mL, 50mL, 100mL, 200mL syringe, 300mL, 500mL S/S cylinder, jacketed glass cylinder or online |
| Cylinder |
Titanium high pressure cylinder (resistant to strong acid and base) |
| |
Varieties of Inlet and Outlet for MixGenizer
Inlet: syringe; open container; stainless steel cylinder
Outlet: syringe; open container; stainless steel cylinder
Genizer's flow Sorter for MixGenizer can collect samples with designed pressure or volume.
A flow sorter allows the user to select (gate) a flow based on pressure or volume.
The user can set the pressure, so the mixed sample above the pressure and mixed sample below the pressure can be separated.
The user can also set the percentage of volume, so the mixed sample within the percentage of volume and mixed sample outside
the percentage of volume can be separated.
Troubleshooting:
Our design has minimized the occurrence of air-blocking, chamber-blocking and overload.
However, the improper operation of the homogenizer can still induce the errors and cause damage to the homogenizer.
Air Blocking
Symptom: there is no pressure and no sucking from inlet
Prevention: do not run with empty inlet
Reason: there is air inside the pump
Solutions:
1. No sucking: Excessive air may be drawn into the high-pressure cylinder, and the air needs to be released. Use a thin wire to gently press the valve ball until the trapped air bubbles are discharged. Alternatively, remove the material inlet check valve and gently shake it to release the air.
2. No pressure: After the material is drawn into the inlet, the liquid level rebounds and homogenization pressure cannot be generated. This indicates that particles are stuck in the inlet check valve, preventing proper sealing. Clean the check valve using an ultrasonic cleaner, rinse with purified water, then reinstall and test again.
Chamber Blocking
Symptom: overload of the pressure
Prevention: pre-treat the sample carefully; reduce the speed
Reason: there are aggregates or particles in the sample; too high a speed
Solutions:
The interaction chamber or high-pressure filter valve may be blocked, which can cause a sudden or abnormal increase in pressure. Reverse-install the high-pressure filter valve and the interaction chamber one by one, then start the machine to clear the blockage. After the blockage is removed, reinstall them in the original direction for normal operation.If the same material frequently causes blockage, consider using a larger-orifice interaction chamber, or pre-treat the material with a high-shear mixer or colloid mill before homogenization.
Overload
Solutions:
1) Reduce the speed and close the power, wait 30 sec and restart
2) Wash with water or solvent
3) Run with clean and homo-disperse sample
No Response
Symptom: the equipment does not respond when click the “Start” button on the touch screen
Solutions:
1) Turn off the power supply and wait for 30 seconds to restart
2) If there is still no response, please check the power input. The power supply of the equipment is 220V. When the external power supply is 110V, a power converter shall be used. And its INPUT port should connect to 110V while the OUTPUT port connect to 220V
Air blocking rarely causes damage to the NanoGenizer; however, the chamber blocking is harmful to the pump because of overloaded pressure in an instant.
1) Pretreat the sample carefully, and always use a clean and homo-disperse sample
2) Adjust the pressure from low to high
3) For safety, do not point the inlet or outlet of high pressure devices and equipment supplied by Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel or object that may affect safety or induce property loss.
Tips:
For facilitating the user applications, the two ports in the high pressure cylinder of the NanoGenizer are exchangeable for inlet and outlet.
Pressure and chamber selection for various applications with NanoGenizer
| Cells |
Mammalian cell
 |
Insect cell |
Bacteria cell |
Yeast cell |
Algae cell |
Spore
 |
| Sample |
CHO|Hela |
Sf9|Sf21|H5 |
E. Coli |
Yeast |
Green algae |
Ganoderma |
| Pressure |
600-800bar 8500-11500psi |
600-1000bar 8500-14500psi |
800-1000bar 11500-14500psi |
1200-1400bar 17500-20000psi |
1200-1500bar 7500-21500psi |
1300-1600bar 18500-23000psi |
| Chamber |
F20Y, F20Y-RT |
F20Y, F20Y-RT |
F20Y, F20Y-RT |
F20Y, F12Y |
F20Y, F12Y |
F20Y, F12Y |
| Emulsions |
Oil in water emulsions
 |
Water in oil emulsions |
Oil emulsion |
Food |
Liposome (o/w) |
Liposome (w/o)
 |
| Sample |
Fat emulsion |
Cosmetics |
Fuel |
Milk |
DOX |
DNA|lipopolyplex |
| Pressure |
~20,000psi |
~10,000psi |
~20,000psi |
~10,000psi |
~20,000psi |
~8,000psi |
| Chamber |
F20Y, F12Y |
F20Y |
F20Y, F12Y |
F20Y |
F20Y, F12Y |
F20Y |
| Dispersions |
Pigments
 |
Creams |
Battery |
Particle aggregation |
Graphene |
Nanotubes
 |
| Sample |
Inks, Coatings |
Creams |
Lithium/Solar cell |
Nano fibril |
Graphene |
Carbon Nanotubes |
| Pressure |
~25,000psi |
~20,000psi |
~20,000psi |
~25,000psi |
~20,000psi |
~20,000psi |
| Chamber |
F20Y, F12Y |
F20Y, F12Y |
F20Y, F12Y |
F20Y, F12Y |
F20Y, F12Y |
F20Y, F12Y |
1. Order the unit from your local agent (recommended)
2. Add the item to the cart, get an online quote from our website and confirm the order and payment accordingly (recommended and quick)
3. Email us to get a quote
4. Order and pay online from the website if the total amount is under $2,500.00.
USD
949-932-0294 Los Angeles 
Nano@Genizer.com