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Liposome HandExtruder

Description: Hand driven extruder is for formulation of 0.25mL-2.0mL liposome and lipopolyplex; Temperature control is available.
Catalog Number: Cat.HandExtruder™
$1,250.00   Login for Discount
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  • Temperature Control:
    HandExtruder™1mL HandExtruder™1mL-RT
  • Gas Tight Syringe:
    1.0mL*2 0.5mL*2 2.5mL*2
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  • Description
  • How to Use
  • FAQ and Tips
The HandExtruder is a manually powered extruder designed for use with small samples. The sample is passed back through the membrane by pushing the sample back and forth between two syringes. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The HandExtruder is virtually no dead-volume and easily cleaned and suitable for sterilization.
Liposome Extrusion
Low Dead Volume
HandExtruder™-1mL-RT can increase the temperature
Catalog No. HandExtruder™-1mL  HandExtruder™-1mL-RT
Description Liposome Hand Extruder Liposome Hand Extruder with Thermo-Jacket
Cooling None Yes
Dimensions 23cm×17cm×13cm 23cm×17cm×13cm
Weight 2kg 2kg
Application Liposome formulation Lipids with high transition Temp. or heat sensitive
Min. Sample Size 0.25mL
Max. Pressure 130psi
Temperature Limit 80ºC (176ºF)
Power Type Hand Drive
Nano-membrane 19mm polycarbonate membrane
Cleaning Flush to clean
Sterilizing Whole unit autoclavable
Standard Features
Parts 1) Liposome HandExtruder
2) 10 pieces of 100nm membrane
Feed Reservoir 1.0 mL gas-tight syringe
Collector Reservoir 1.0 mL gas-tight syringe
Nano membrane 100nm 19mm track-etched polycarbonate membrane
Compatibility Parts are compatible with Liposofast in Avestin
Product material 316L stainless steel, Viton
Material standard Pharmaceutical Grade
Warranty 1 year against any manufacturing defects
Option Features
Parts Stabilizer holder for Hand Extruder
Feed Reservoir 0.25/0.5/1.0/2.5mL gas tight syringe
Collector Reservoir 0.25/0.5/1.0/2.5mL gas tight syringe
Nano membrane 30, 50, 80, 100, 200, 400, 800nm, 1000nm, 2μm, 5μm, 10μm, 20μm, 30μm 19mm track-etched membrane
Syringe Type Gas-tight syringe with Protective Film
Laboratory Instruction of Hand Liposome Extruder

Disassemble the Hand Extruder, load 1-2 pieces of liposome extruding Nano pore membrane

Connect the gas-tight syringe (0.25mL, 0.5mL, 1mL, 2.5mL) in two end

Load the sample and extruding by press back and forth 10 times


Extruding through 800, 400nm, 200nm, 100nm (if needed 80nm, 50nm, 30nm) nano pore membranes
Considering the limitations of the durability of POM plastic, can the filter chamber be customized with metal material?
Of course, we recommend 316L filter chamber. The stainless steel luer lock is more durable. And the hygienic property, low expansion coefficient, high thermal conductivity, and  hardness of this material can make users experience better.

filter chamberfilter chamber